文章名稱(chēng)引用次數(shù)

• Protac-Induced Protein Degradation in Drug Discovery: Breaking the Rules or Just Making New Ones?78
• Polypharmacology by Design: A Medicinal Chemist's Perspective on Multitargeting Compounds60
• Two Decades under the Influence of the Rule of Five and the Changing Properties of Approved Oral Drugs50
• Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)43
• Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals)42
• Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression40
• Modulators of 14-3-3 Protein-Protein Interactions39
• Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression37
• From Oxiranes to Oligomers: Architectures of US FDA Approved Pharmaceuticals Containing Oxygen Heterocycles35
• Inhibitors of Melanogenesis: An Updated Review31